Efficacy of one-stage cartilage repair using allogeneic mesenchymal stromal cells and autologous chondron transplantation (IMPACT) compared to nonsurgical treatment for focal articular cartilage lesions of the knee: study protocol for a crossover randomized controlled trial
نویسندگان
چکیده
منابع مشابه
Gel-type autologous chondrocyte (Chondron™) implantation for treatment of articular cartilage defects of the knee
BACKGROUND Gel-type autologous chondrocyte (Chondron) implantations have been used for several years without using periosteum or membrane. This study involves evaluations of the clinical results of Chondron at many clinical centers at various time points during the postoperative patient follow-up. METHODS Data from 98 patients with articular cartilage injury of the knee joint and who underwen...
متن کاملAutologous-cell-derived, tissue-engineered cartilage for repairing articular cartilage lesions in the knee: study protocol for a randomized controlled trial
BACKGROUND Spontaneous recovery from articular cartilage injury is difficult, and the ongoing progression of disease can eventually lead to osteoarthritis. Currently, there is no effective non-surgical treatment for articular cartilage injury. Arthroscopic debridement and microfracture surgery are performed for fibrocartilage repair. But fibrocartilage is different from normal articular cartila...
متن کاملAutologous Chondrocyte Implantation for Focal Articular Cartilage Lesions
PLEASE NOTE: Contracts exclude from coverage, among other things, services or procedures that are considered investigational or cosmetic. Providers may bill members for services or procedures that are considered investigational or cosmetic. Providers are encouraged to inform members before rendering such services that the members are likely to be financially responsible for the cost of these se...
متن کاملAutologous Chondrocyte Implantation for Focal Articular Cartilage Lesions
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متن کاملAutologous Chondrocyte Implantation for Focal Articular Cartilage Lesions
When Policy Topic is covered Autologous chondrocyte implantation may be considered medically necessary for the treatment of disabling full-thickness articular cartilage defects of the knee caused by acute or repetitive trauma, in patients who have had an inadequate response to a prior surgical procedure, when all of the following criteria are met: Adolescent patients should be skeletally matu...
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ژورنال
عنوان ژورنال: Trials
سال: 2020
ISSN: 1745-6215
DOI: 10.1186/s13063-020-04771-8